The assembly of the Bread wheat genome has extreme challenges including its large genome size (16 giga bp), a high level of repetitive sequences (>85%) and its hexaploid genome structure. Yet, sequence costs and genome assembly methodologies have made great advancements over the past few years to enable high-quality reference genome assemblies of complex genomes from short read data. this was demonstrated with the successful high-quality assembly of wheat genomes using NGS data and NRGene’s DenovoMAGIC algorithms including the wild-emmer wheat, followed by the bread- wheat var. Chinese-spring, and the durum wheat var Svevo. Using independent quality checks, these genome assemblies have been shown to be some of the highest quality large plant genome assemblies as indicated by multiple measures and statistics. 15 more bread wheat cultivars were assembled in the past years using DeNovoMAGIC, and the comparison of all those genomes enables us to follow both evolution and domestication of the world most consumed crop.