Climate change is expected to result in more severe abiotic and biotic stresses, especially in the West Asia and North Africa region (WANA). Therefore, wheat breeding programs will need to accelerate their response to these changing conditions. Speed breeding has been mostly used to accelerate spring wheat breeding cycle while its use in facultative and winter wheat is still limited, mostly due to the vernalization requirements and the complexity of its phenological response to the environment. To explore the potential of Speed Breeding in winter wheat for the WANA region and its impact in the resulting varieties’ phenology and adaptation, a set of 240 winter and facultative wheat genotypes from the International Winter Wheat Improvement Program (IWWIP) was assembled and genotyped. The set was tested at the ICARDA Speed Breeding facilities in Morocco under long vernalization (45 days at 50C) and photoperiod (19/5 day/night hours) conditions. Additionally, the set was tested for flowering date in 14 environments in Spain and Morocco and in yield trials in 10 environments of Turkey, Iran and the highlands of Morocco. The results showed that the average cycle duration from planting to mature grain under Speed breeding was 124 days and 55% of the genotypes had cycles equal or shorter than 122 days, that is, they could achieve 3 generations per year. In field conditions the average days to maturity were 240. The results also showed significant correlations between the days to heading under Speed Breeding and the 10 environments analyzed. The correlation was higher (up to r=0.52; p<0.001) in environments with low initial temperatures and high temperatures during stem elongation. Additionally, genomic selection prediction accuracies for phenology in the 10 yield trials were obtained through ridge regression best linear unbiased prediction using the flowering date experiments as training locations and the weather data to refine the adjustment. Significant correlations between the GEBV and the yield trial phenologies were found. In conclusion, Speed Breeding is a potential tool to accelerate winter wheat breeding in WANA by up to three-fold. However, there could be a potential bias in the resulting genotypes if a strict selection for early flowering plants under Speed Breeding conditions – that is, plants that can achieve 3 generations per year - was applied at segregating population stage. A step of genomic selection for flowering date applied during the speed breeding process can help improving the adaptation to the target environments.