Fusarium head blight (FHB) is a devastating fungal disease of small-grain cereals that results in severe yield and quality losses. The most effective solution to address FHB is to develop resistant cultivars. FHB resistance is achieved through components such as: incidence, field severity, index, DON toxin accumulation, fusarium damaged kernels (FDK) and spreading (greenhouse). These confer partial resistance and combining different resistance components is necessary to achieve the desired level to protect from yield losses. However, there is limited information about the genetic architecture underlying these resistance components and the effects they contribute to FHB resistance. Here, a detailed analysis of resistance components was undertaken through the study of multiparental mapping populations targeted for FHB resistance. More than 40 QTL associated with different resistant components were identified, including QTL on chromosome arms 2A, 4A , 4B and Fhb1 on 3B that consistently contributed to the majority of FHB resistant components across populations, years and sites. Fhb1 contributed the largest effects towards FHB severity, FDK and DON, but not for incidence and greenhouse spreading. The interaction of FHB component traits with phenology-related traits such as those that flowering time, vernalisation and photoperiod as well as plant height, known to influence FHB resistance, was also investigated. With the exception of Fhb1, all other FHB resistance QTL identified were associated with phenology-related traits. The importance of Fhb1 prompted us to further analyze genes within the Fhb1 region in different genetic backgrounds. Analysis of PFT genes in diverse genotypes suggests that it may be not associated with FHB resistance. Two homeologous HRC genes of the susceptible type were identified on chromosome arms 3B and 3D. These are being analyzed in more detail.