Heat and drought stresses are main threats to wheat production worldwide especially due to climate change. Quantitative trait loci (QTL) analysis was carried out on 143 recombinant inbred lines derived from a cross between the spring wheats Kauz and MTRWA116 to identify genomic regions controlling yield and yield related traits. The population was grown under normal, drought and heat stress conditions in the United States and Iran in 9 site × year × treatment combinations. 231 SSR, 267 AFLP, 2 Rht specific PCR and 1 kernel color markers were used to construct a linkage map covering 20 chromosomes. With the method of composite interval mapping 6, 6, 2, 4, and 2 constant QTLs were detected for grain yield, 1000 kernel weight, grain filling duration, peduncle length and plant height respectively. A QTL flanked by Rht-D1 on chromosome 4D, contributed to grain yield, 1000 kernel weight, kernels per spike, plant height, and peduncle length under heat, drought, and normal conditions while a QTL near Rht-B1 on chromosome 4B controlled all the same traits except kernels per spike. A QTL on chromosome 2B closely linked to gwm232a and gwm148 was detected for heat tolerance in terms of yield under stress.