Wheat growth is sensitive to temperature, but the effect of future warming on yield is uncertain. Here, focusing on China, we compiled 46 observations of the response of wheat yield to temperature change (SY,T, yield change per oC) from field warming experiments and 102 SY,T estimates from local process-based and statistical models. The average SY,T from field warming experiments, local process-based models and statistical models is -0.7±7.8% (±s.d.) per oC, -5.7±6.5% per oC and 0.4±4.4% per oC, respectively. Moreover, SY,T is different across regions and warming experiments indicate positive SY,T values in regions where growing-season mean temperature is low, and water supply is not limiting, and negative values elsewhere. Gridded crop model simulations from the Inter-Sectoral Impact Model Intercomparison Project appear to capture the spatial pattern of SY,T deduced from warming observations. These results from local manipulative experiments could be used to improve crop models in the future.